NeoGen Plasma Skin Regeneration in Appleton, WI
NeoGen Plasma Skin Regeneration is an FDA-cleared, non-surgical treatment that uses nitrogen plasma energy to rejuvenate the skin from within. It is the first and only clinically studied method of full skin regeneration, and it is safe for every skin type. At Wisconsin Institute of Functional Medicine in Appleton, we use NeoGen to soften wrinkles, correct pigment, improve scarring, and tighten loose skin, often in a single procedure, with results may continue to improve for an extended period as new collagen forms and the skin regenerates.
Below is everything you need to know before booking a consultation.

What is NeoGen plasma skin regeneration?
NeoGen is a non-surgical skin regeneration treatment that uses nitrogen plasma technology instead of traditional light-based laser treatments or needles It is FDA-cleared and is recognised as the first and only clinically proven method for complete skin regeneration.Â
Unlike treatments that resurface the skin by removing its outer layer, NeoGen works underneath it. The surface stays intact and acts as a natural protective dressing while the skin rebuilds from the inside. That is why NeoGen can be used safely on all skin types, including darker skin tones, where many resurfacing lasers carry a risk of pigmentation.
A single NeoGen procedure can address wrinkles, sun damage, pigmentation, acne scarring, scarring on the face and body, loose eyelid skin, dark circles under the eyes, and enlarged pores.

How does NeoGen work?
NeoGen converts nitrogen gas into plasma energy and delivers it as controlled pulses just below the surface of the skin. That energy triggers your body’s own healing response. Collagen and elastin production is stimulated, existing tissue tightens, and fresh, healthy skin begins to form.
Because the outer layer of skin is not removed, it remains in place as a natural dressing while regeneration happens beneath it. The old surface sheds naturally over the following days, revealing the new skin underneath.
The energy level is set by your clinician. Lower settings mean gentler treatment and shorter downtime. Higher settings drive deeper regeneration and take longer to recover from. This is the single most important thing to understand about NeoGen: it is not one fixed treatment, it is a spectrum, and the setting is chosen to match your skin, your concerns, and how much downtime you can accommodate.

What can NeoGen treat?
NeoGen is used to address:
- Fine lines and deep wrinkles. Collagen and elastin stimulation smooths the surface and softens set-in lines.
- Skin laxity. Existing tissue tightens during treatment, with further firming as new collagen forms.
- Pigmentation and sun damage. Age spots, sun spots, and uneven tone are evened out.
- Acne scarring and other scarring. On the face and on the body.
- Loose eyelid skin. NeoGen can be used safely on the upper and lower eyelids, an area most resurfacing devices cannot treat without surgery.
- Dark circles under the eyes.
- Enlarged pores and overall skin texture.

Is NeoGen safe for all skin types?
Yes. NeoGen’s energy settings are adjustable, and because the treatment does not ablate the surface of the skin, it does not carry the post-inflammatory hyperpigmentation risk that limits many laser resurfacing treatments in darker skin tones.
This is one of the clearest points of difference between NeoGen and a conventional resurfacing laser, and it is the reason we are able to offer it to patients who have been told they are not a candidate for other skin rejuvenation treatments.

What happens during a NeoGen treatment at our Appleton clinic?
A session lasts between 10 and 60 minutes, depending on the size of the area being treated and the energy setting used. A topical anaesthetic can be applied on request.
Most patients describe the sensation as a wave of heat rather than a sharp or stinging pain. There are no needles and no incisions.
You will leave the same day. There is no general anaesthetic, no sedation, and no need for someone to drive you home.

What does recovery from NeoGen look like?
Recovery is determined by the energy setting used:
- Lower settings: typically a few days of social downtime. Skin feels tight and looks flushed, then flakes.
- Higher settings: up to around a week of social downtime, with more pronounced peeling as the old surface sheds.
Because the outer layer of skin remains in place throughout, there is no open wound to care for, which is a meaningful difference from ablative laser resurfacing.
Your clinician will talk you through aftercare, including sun protection, which matters a great deal while new skin is forming.

When will you see results from NeoGen?
You will see surface improvements within days of the old skin shedding. The deeper changes, the collagen and elastin remodelling, continue to develop for up to 24 months after a single procedure.
This is what separates NeoGen from most aesthetic treatments. You are not maintaining a result. You are regenerating tissue, and that tissue keeps improving long after you have left the clinic.
How is NeoGen different from lasers, microneedling, and chemical peels?
| Treatment Feature | NeoGen Plasma | Ablative Laser | Microneedling | Chemical Peel |
|---|---|---|---|---|
| Outer skin layer | Left intact as a natural dressing | Removed | Punctured | Chemically shed |
| Safe for all skin types | Yes | Often limited in darker skin tones | Generally yes | Varies by peel depth |
| Eyelid skin | Yes | Rarely | Limited | No |
| Results continue for | Up to 24 months | Months | Months | Weeks to months |
| Sessions for a full result | Often a single procedure | Often multiple | Typically a course | Typically a course |


Who is a good candidate for NeoGen?
NeoGen suits you if you want visible, lasting skin rejuvenation without surgery, injectables, or a long course of appointments, and you can accommodate a short period of social downtime.
It is particularly worth considering if:
- You have been told your skin type rules you out of laser resurfacing.
- You want the loose skin on your eyelids addressed without surgery.
- You would rather have one meaningful procedure than a standing course of maintenance treatments.
The only way to know for certain is a consultation. Skin, medical history, and goals all factor into the energy setting and into whether NeoGen is the right choice at all.

Why have NeoGen at Wisconsin Institute of Functional Medicine?
Most aesthetics clinics look at your skin. We look at what is driving it.
Skin is an output. Hormones, inflammation, nutrient status, sleep, and metabolic health all show up in it. As a functional medicine practice, we are set up to look at those inputs alongside the treatment itself, which means the result you get from NeoGen is supported from the inside as well as the outside. Where it is part of your care, that can include laboratory testing and body composition scanning as part of a broader picture of your health.
Your treatment is delivered under the supervision of Dr. Tracy Page at our clinic on East Enterprise Avenue in Appleton, serving patients across the Fox Valley including Neenah, Menasha, Kaukauna, Oshkosh, and Green Bay.

How many NeoGen sessions will you need, and what does it cost?
We offer a variety of NeoGen treatment options, and the number of sessions recommended will depend on your individual skin concerns and goals. Most patients begin with a single treatment session.
A typical session is $3,500 for face and neck. Face only is $2,500, neck only is $1,000, and décolleté only is $1,000. Targeted areas are $650, and we also offer a lip plumpness package of 6 treatments for $450.
NeoGen before and after
Introducing a New Era of Skin Renewal
Ready to Find Out Whether NeoGen Is Right for Your Skin?
Frequently asked questions about NeoGen
Am I a good candidate for NeoGen treatment?
Most people are. NeoGen is safe for all skin types, including darker skin tones, because it does not remove the surface layer of the skin. A consultation is needed to confirm, as your medical history, current medications, and skin condition all factor into whether NeoGen is appropriate and at what energy setting.
What areas can be treated with NeoGen?
The face, including the delicate skin of the upper and lower eyelids, and the body. It is commonly used on the face, neck, décolletage, and hands, and it can be used on scarring elsewhere on the body.
How much time will it take to recover after NeoGen treatment?
It depends on the energy setting. Lower settings usually mean a few days of social downtime. Higher settings can mean up to a week. The outer skin layer stays intact throughout, so there is no open wound to manage.
When will I see results from NeoGen?
Surface improvements appear within days, once the treated skin has shed. The deeper collagen and elastin remodelling continues to build for up to 24 months after a single procedure.
Is NeoGen treatment painful?
Most patients describe it as a sensation of heat rather than pain. A topical anaesthetic can be applied on request before treatment.
How does NeoGen work?
It converts nitrogen gas into plasma energy and delivers it beneath the surface of the skin, triggering your body’s natural healing response. Collagen and elastin production is stimulated, existing tissue tightens, and new skin forms while the outer layer remains intact as a protective dressing.
Is NeoGen the same as a laser?
No. Lasers use light energy and typically ablate, or remove, the outer layer of skin. NeoGen uses nitrogen plasma and leaves the outer layer in place. This is why it can be used safely on skin types and areas, such as the eyelids, where lasers often cannot.
How many NeoGen treatments will I need?
[TBD: WIFM to confirm. Many patients see a full result from a single procedure, but this depends on the concern being treated and the energy setting used.]
Is there anything I should avoid before or after NeoGen?
Yes. Sun exposure is the main one, both before treatment and while your skin is regenerating afterwards. Your clinician will give you a full aftercare plan at your consultation, including any medications or topical products to pause.
Can I have NeoGen if I have had other skin treatments?
In most cases, yes, though timing matters. Tell your clinician about any recent injectables, peels, laser treatments, or prescription skincare at your consultation.













